Saharan-Arabian area covers the northern part of Africa, mainly part of the Arabian Peninsula and small part of south-western Asia. Flora is rather poor here, because its considerable part contains desert areas with low species diversity. A bit richer is only the area in Ethiopia with 2 endemic plant families. In the northern part is considerable attachment to the Holarctis.
- ANCHUSA AEGYPTIACA (L.) A. DC. – Egyptian Alkanet
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- ERICA ARBOREA L. – Brierroot, Tree Heath
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- EUPHORBIA BALSAMIFERA Ait.
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- EUPHORBIA GLOCHIDIATA Pax
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- GOMPHOCARPUS FRUTICOSUS (L.) W. T. Aiton – Narrow-leafed Cotton Bush, Swan Plant, Bristle-fruited Silkweed, Mobydick
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- PLANTAGO AFRA L. – African Plantain, Glandular Plantain, Black Psyllium
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- PLANTAGO ALBICANS L. – Downy Plantain
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