Caribbean covers whole Mesoamerica with the islands in Caribbean sea and also Galápagos. This area is botanically rich; it has some endemic families and high representation of endemic species. Caribbean is marginally influenced by the vegetation of Paleotropis and Holarctis.
- AECHMEA BRACTEATA (Sw.) Griseb.
- AECHMEA NUDICAULIS (L.) Griseb.
- ALISMA PLANTAGO-AQUATICA L. – Common Water-plantain
- ALLOISPERMUM INTEGRIFOLIUM (DC.) H. Rob.
- BEGONIA HERACLEIFOLIA Cham. et Schltdl. – Starleaf Begonia
- BLUTAPARON VERMICULARE (L.) Mears – Silverweed, Saltweed, Samphire
- BRASSIA VERRUCOSA Bateman ex Lindl. – Warty Brassia
- CAESALPINIA PULCHERRIMA (L.) Sw. – Poinciana, Peacock Flower, Red Bird of Paradise, Mexican Bird of Paradise, Dwarf Poinciana, Pride of Barbados, Flamboyan-de-jardin
- CAPSICUM LANCEOLATUM (Greenm.) C. V. Morton et Standl.
- CEIBA PENTANDRA (L.) Gaertn. – Kapoktree, Silk Cottontree
- CENTROSEMA ANGUSTIFOLIUM (Kunth) Benth.
- CENTROSEMA PLUMIERI (Pers.) Benth. – Feefee
- CENTROSEMA SCHOTTII (Millsp.) K. Schum.
- CORALLORHIZA MACULATA (Raf.) Raf. – Spotted Coralroot, Western Coralroot, Summer Coralroot
- DAHLIA IMPERIALIS Roezl ex Ortgies – Tree Dahlia
- DALBERGIA ECASTAPHYLLUM (L.) Taub. – Coinvine
- DALECHAMPIA SCHIPPII Standl.
- ECHINODORUS SUBALATUS (Mart. ex Schult. f.) Griseb.
- GLANDULARIA BIPINNATIFIDA (Schauer) Nutt. – Southwestern Mock Vervain, Dakota Verbena
- GUZMANIA MONOSTACHIA (L.) Rusby ex Mez
- GUZMANIA SANGUINEA (André) André ex Mez
- HAEMATOXYLUM CAMPECHIANUM L. – Logwood
- HELIANTHUS ANNUUS L. – Common Annual Sunflower, Sunflower, Wild Sunflower
- HYLOCEREUS UNDATUS (Haw.) Britton et Rose – Belle-of-the-night, Nightblooming Cactus, Red Pitaya, Dragon Fruit
- IPOMOEA ALBA L. – Moonflower, Moon Vine, Tropical White Morning-glory
- IPOMOEA IMPERATI (Vahl) Griseb. – Beach Morning Glory
- IPOMOEA PES-CAPRAE (L.) R. Br. – Railroad Vine, Bayhops
- IPOMOEA QUAMOCLIT L. – Cypress Vine, Cardinal Creeper, Cardinal Vine, Star Glory, Hummingbird Vine, Cypressvine Morning Glory
- LIQUIDAMBAR STYRACIFLUA L. – Sweetgum, American Sweetgum, Hazel Pine, Bilsted, Red-gum, Satin Walnut, Star-leaved Gum, Alligator Wood
- LOPEZIA RACEMOSA Cav.
- MACROPTILIUM ATROPURPUREUM (DC.) Urb. – Purple-bean, Surple-bean
- MATELEA LASIOSTEMMA (Hemsl.) Shinners – Milkvine
- MERREMIA UMBELLATA (L.) Hallier f. – Hogvine
- MONOTROPA UNIFLORA L. – Indian-pipe, Ghost Plant, Corpse Plant
- MORELLA CERIFERA (L.) Small – Bayberry, Candleberry, Wax Myrtle
- NYMPHAEA AMPLA (Salisb.) DC. – Dotleaf Waterlily
- PARTHENIUM HYSTEROPHORUS L. – Bitterweed, Carrot-grass, Santa Maria Feverfew
- PASSIFLORA ORNITHOURA Mast.
- PLEOPELTIS POLYPODIOIDES (L.) E. G. Andrews et Windham – Resurrection Fern
- PLUCHEA CAROLINENSIS (Jacq.) G. Don – Cattletongue, Coughbush, Cure-for-all
- PONTEDERIA CORDATA L. – Pickerelweed
- POSOQUERIA LATIFOLIA (Rudge) Schult. – Needle Flower Tree
- PROSTHECHEA COCHLEATA (L.) W. E. Higgins – Cockleshell Orchid, Clamshell Orchid, Black Orchid
- PROSTHECHEA OCHRACEA (Lindl.) W. E. Higgins
- RUMOHRA ADIANTIFORMIS (G. Forst.) Ching – Leather Fern, Leatherleaf Fern
- SAGITTARIA LATIFOLIA Willd. – Wapato, Common Arrowhead, Duck-potato, Broadleaf Arrowhead, Indian Potato
- SALVINIA MINIMA Baker – Common Salvinia, Water Spangles, Floating Fern
- SCHIZOLOBIUM PARAHYBA (Vell.) S. F. Blake – Brazilian Firetree, Quamwood
- SELENICEREUS ANTHONYANUS (Alexander) D. R. Hunt – Fish Bone Cactus, Rick Rack Cactus, Zig-zag Cactus, St. Anthony’s Rik-Rak
- SESUVIUM PORTULACASTRUM (L.) L. – Seaside Purslane, Shoreline Purslane, Sea Purslane
- SYMPHYOTRICHUM LAEVE (L.) Á. Löve et D. Löve – Smooth Aster, Glaucus Aster
- TILLANDSIA CAPUT-MEDUSAE E. Morren – Medusa’s Head, Octopus Plant
- TILLANDSIA COMPRESSA Bertero ex Schult. et Schult. f.
- TILLANDSIA FASCICULATA Sw. – Giant Air Plant
- TILLANDSIA USNEOIDES (L.) L. – Spanish Moss, Long Moss, Black Moss, Old Man’s Beard
- TRADESCANTIA SPATHACEA Sw. – Moses-in-the-cradle, Boat-lily, Oysterplant
- WALTHERIA INDICA L. – Uhaloa, Boaterbush, Sleepy-morning, Buff-coat
- WERNERIA NUBIGENA Kunth